Wellbutrin (bupropion) is used to treat major depressive disorder and seasonal affective disorder. Includes Wellbutrin side effects, interactions and indications. Find patient medical information for Bupropion (Wellbutrin, Zyban, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Bupropion, formerly called amfebutamone, [17] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder and seasonal affective disorder and to support smoking cessation. [18][19] It is a norepinephrine–dopamine reuptake inhibitor (NDRI). Wellbutrin is prescribed to treat major depressive disorder and prevent seasonal affective disorder. Learn about the drug’s dosages and more. Read on for bupropion dosage information, including typical dosage, adjustments for health conditions, and what to do if you miss a dose. Medical information for Wellbutrin XR including its dosage, uses, side, effects, interactions, pictures and warnings. Wellbutrin® Xr is sold under different brand names. If you are already taking medicine for depression or to help you stop smoking, discuss this with your doctor before taking Wellbutrin® Xr. It is very important that you receive only one prescription at a time for Wellbutrin® Xr. Wellbutrin® Xr is available only with your doctor's prescription. Bupropion is an antidepressant used for depression, seasonal affective disorder, smoking cessation, and weight loss by targeting dopamine and norepinephrine. Wellbutrin XL (Bupropion Hydrochloride Extended-Release) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Wellbutrin SR and XL are both used to treat depression, but they have other FDA-approved uses that are different. They’re also taken differently.